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doctoral thesis
Bolesti usne šupljine: prevalencija i povezanost s koronarnom bolesti srca
doktorski rad
2012. urn:nbn:hr:188:284537
Prpić, Jelena
University of Rijeka
Faculty of Medicine

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Prpić, J. (2012). Bolesti usne šupljine: prevalencija i povezanost s koronarnom bolesti srca : doktorski rad (Doctoral thesis). Rijeka: University of Rijeka, Faculty of Medicine. Retrieved from https://urn.nsk.hr/urn:nbn:hr:188:284537

Prpić, Jelena. "Bolesti usne šupljine: prevalencija i povezanost s koronarnom bolesti srca : doktorski rad." Doctoral thesis, University of Rijeka, Faculty of Medicine, 2012. https://urn.nsk.hr/urn:nbn:hr:188:284537

Prpić, Jelena. "Bolesti usne šupljine: prevalencija i povezanost s koronarnom bolesti srca : doktorski rad." Doctoral thesis, University of Rijeka, Faculty of Medicine, 2012. https://urn.nsk.hr/urn:nbn:hr:188:284537

Prpić, J. (2012). 'Bolesti usne šupljine: prevalencija i povezanost s koronarnom bolesti srca : doktorski rad', Doctoral thesis, University of Rijeka, Faculty of Medicine, accessed 06 December 2024, https://urn.nsk.hr/urn:nbn:hr:188:284537

Prpić J. Bolesti usne šupljine: prevalencija i povezanost s koronarnom bolesti srca : doktorski rad [Doctoral thesis]. Rijeka: University of Rijeka, Faculty of Medicine; 2012 [cited 2024 December 06] Available at: https://urn.nsk.hr/urn:nbn:hr:188:284537

J. Prpić, "Bolesti usne šupljine: prevalencija i povezanost s koronarnom bolesti srca : doktorski rad", Doctoral thesis, University of Rijeka, Faculty of Medicine, Rijeka, 2012. Available at: https://urn.nsk.hr/urn:nbn:hr:188:284537

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Metadata
TitleBolesti usne šupljine: prevalencija i povezanost s koronarnom bolesti srca : doktorski rad
Title (english)Diseases of the oral cavity: their prevalence and relationship with coronary heart disease : doctoral thesis
AuthorJelena Prpić
MentorSonja Pezelj-Ribarić (mentor)
Committee memberIvica Anić (predsjednik povjerenstva)
Committee memberLuka Zaputović (član povjerenstva)
Committee memberMaja Abram (član povjerenstva)
Committee memberSonja Pezelj-Ribarić (član povjerenstva)
GranterUniversity of Rijeka
Faculty of Medicine
Rijeka
Defense date and country2012-02-20, Croatia
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Dental Medicine
Universal decimal classification
(UDC)		616.31 - Stomatology
Abstract
Cilj istraživanja: koronarna srčana bolest je većinom uzrokovana aterosklerozom. U patogenezi ateroskleroze glavnu ulogu igra upala, odnosno poremećen upalni odgovor. Budući da je usna šupljina infekcijom vrlo bogato mjesto, te se u njoj razvijaju i neke upalne neinfektivne lezije, cilj straživanja je bio utvrditi prevalenciju najčešćih bolesti usne šupljine, te ih povezati s koronarnom srčanom bolesti. Ispitanici i metode: ispitivanu skupinu činilo je 143 pacijenta s dijagnozom koronarne srčane bolesti; 149 ispitanika kontrolne skupine regrutirano je pri Klinici za dentalnu medicinu KBC Rijeka. Svakom ispitaniku utvrđena je aktivnost karijesa, parodontalne bolesti te lezija oralne sluznice, te je uzet bris za Candidu albicans. Ostali nalazi su uključivali visinu, težinu, te analizu krvi. Ispitanici su popunili upitnik s općim podacima, oralno-higijenskim navikama, te ljekovima koje uzimaju. Rezultati: Prevalencija infektivnih bolesti zuba i potpornih tkiva je bila vrlo visoka. Osobe s koronarnom srčanom bolesti imaju lošije oralno-higijenske navike i oralno zdravlje; češće imaju prekomjernu težinu, povišene trigliceride i ALT, osjećaj suhih usta i pečenja, te češće pate od lezija oralne sluznice. Čak 50% ispitanika ima povišene razine kolesterola. Zaključak: infektivne bolesti zuba mogle bi biti povezane s rizikom od razvoja koronarne srčane bolesti. Najvažniji su aktivnost karijesa i gubitak zuba, dok stupanj parodontitisa nema utjecaja. Mogući čimbenici koji utječu na tu povezanost su razina leukocita i triglicerida – navedeno podržava hipotezu o upalnoj reakciji kao podlozi ateroskleroze. Potrebno je ustanoviti mjere primarne i sekundarne prevencije kojima bi se ranom dijagnozom problema u usnoj šupljini i njihovim liječenjem smanjio mogući bakterijski i upalni teret.
Abstract (english)
Objectives: coronary heart disease is mostly cause by atherosclerosis. Tha major role in atheroscelrosis is played by inflammation and altered immune response. Since oral cavity is loaded with infective agents, but is also the site of some inflammatory non-infective lesions, objective of this investigation was to determine prevalence of most common mouth diseases, and to correlate them with coronary heart disease. Patients and Methods: Experimental group included 143 patients diagnosed with coronary heart disease; 149 control subjects were recruited from the Clinic for dental medicine of clinical Hospital Center Rijeka. Every patient was assessed regarding the caries activity, periodontal disease and oral lesions, and swabs were taken for detection of Candida albicans. Other parameters included heigth, weight and blood analysis. Patients filled out a questionnaire on general data, oral hygiene routines, and medications taken. Results: Prevalence of infectious tooth and periodontal diseases was very high. Patients with coronary heart disease had worse oral hygiene and oral health; they were more likely to be overweight, to have increased triglycerides and ALT, to suffer from dry mouth and burning mouth syndrommes, and to have oral lesions. As much as 50% of the subjects had elevated cholesterol levels. Conclusion: Infectious tooth diseases may be connected to the risk of coronary heart disease. The most important factors are the levels of leukocytes and triglycerides – this supports the hypothesis of inflammation in pathogenesis of atherosclerosis. It will be necessary to found measures of primary and secondary prevention in order to decrease bacterial and inflammatory load through the early diagnosis and timely treatment of oral and tooth diseases.
Keywords
Keywords (english)
Languagecroatian
URN:NBNurn:nbn:hr:188:284537
Study programmeTitle: Biomedicine Postgraduate (doctoral) study programme
Study programme type: university
Study level: postgraduate
Academic / professional title: doktor/doktorica znanosti, područje biomedicine i zdravstvo (doktor/doktorica znanosti, područje biomedicine i zdravstvo)
Catalog URLhttp://libraries.uniri.hr/cgi-bin/ucat/unilib.cgi?form=D1121123028
Type of resourceText
Extent111 str; 30 cm
File originBorn digital
Access conditionsOpen access
Terms of useLicence Attribution-ShareAlike 4.0 International (CC BY-SA 4.0) icon
Public noteRad ne sadrži ključne riječi. Ključne riječi unio urednik repozitorija.
Created on2017-01-19 19:01:04